Love this feature! Yahoo released the possibility to explore charts with audio, in the finance app, when using screen readers in 2019. You can do now something very similar since iOS 15.

You can move your finger in the x-axes, and it will play a sound with a different pitch depending on the data in the y-axes, making it easier to identify trends in the graphs.
You need to conform to the AXChart protocol by implementing the accessibilityChartDescriptor property.
Documentation: https://developer.apple.com/documentation/accessibility/audio-graphs
WWDC21 session: https://developer.apple.com/videos/play/wwdc2021/10122/
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You don't have to offer an alternative layout just for the accessibility category. You can actually compare content size categories. So you could tweak the UI already for anything equal to or larger than .extraExtraLarge, for example.

"We have one job, and that's to make our apps work. And if you are not implementing accessibility features, you are forgetting about making it work for a lot of people" @NovallSwift Couldn't have said it better! https://x.com/novallswift/status/1328387659744505856
If you want to keep yourself up to date with what’s going on, or what has been published lately, on how to develop more accessible mobile apps, make sure you subscribe to Accessible Mobile Apps Weekly by @RobinKanatzar from @accessible_apps.