Abstracting your interface in a way that can offer multiple input and output mechanisms is key when developing software with an accessibility mindset. Apple has brought this to the next level in visionOS.
Create accessible spatial experiences
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Check isReduceTransparencyEnabled to lower transparency. A great example is Spotlight. Not only transparency is removed but it keeps the main color of the background, it feels personalized and contextual but reduces noise and improves contrast.
Make sure you support Dynamic Type up to the largest text size available. Take into account that there are five extra accessibility sizes available from the Accessibility Settings. It can make a huge difference for lots of users.
Support both orientations, if possible. I know not even iOS itself does it, but it hasn't always been like that. You'll create a more robust UI that will be easier to port to iPadOS. And especially, don't force your users to rotate their devices.
