An alternative layout for large font sizes can be provided with Auto Layout by having three sets of constraints (common, default constraints, and alternative constraints) and activate/deactivate them depending on the content size category.
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Potential benefits from grouping logical pieces of information and moving buttons to custom actions: reduce redundancy (by removing repetitive controls) and reduce cognitive load (by making easier to know what item will be affected by each action)
Touch target sizes are recommended to be at least 44 x 44 points. Buttons in the navigation bar ( especially when not using nav bar button items), dismiss buttons, and custom toolbars, are use cases that tend to have smaller sizes.
When implementing a UISlider, it is a good idea to consider how much the slider value should change when swiping up/down to adjust it. It might not always make sense to do it in 10% increments, which is the default behaviour. Could be because the value at those intervals doesn't make sense, or feel random, or because it wouldn't provide the user with a fine enough control being able to go through the whole slider in just 10 swipes. It user will still be able to adjust the slider to any value by double tapping and holding and then moving the finger left or right, bypassing VoiceOver gestures. VoiceOver announces the new value as it changes.
