Good accessibility labels are at the core of good accessible apps. It should be a localized succinct string that tells as much as possible about the component (without including its type) and provides context avoiding verbosity and redundancy.
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Do you have a fancy custom loading animation instead of an UIActivityIndicatorView? You may want to check if it has an accessibility label so a VoiceOver user knows that something is happening. Something like "In progress" or "Loading" could work.
@NSSpain has a great history of having amazing accessibility talks in their schedule! “Accessibility in the Real World”, by @Sommer: https://vimeo.com/235317172 “How to build an app for everyone”, by @NovallSwift: https://vimeo.com/362163043 The super fun "Choose your own SwiftUI adventure - 3 Accessibility", by @twostraws and @PinkerStraws: https://vimeo.com/481768105 And, of course, this year's great "Bas: My Accessibility Story", by @basthomas: https://vimeo.com/751176747
Check isReduceTransparencyEnabled to lower transparency. A great example is Spotlight. Not only transparency is removed but it keeps the main color of the background, it feels personalized and contextual but reduces noise and improves contrast.