If, for some reason, you are creating a button from scratch, instead of relying on UIButton (perhaps you are adding a fancy micro interaction animation?), take into account that you’ll need to configure the button accessibility trait.
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When implementing a UISlider, it is a good idea to consider how much the slider value should change when swiping up/down to adjust it. It might not always make sense to do it in 10% increments, which is the default behaviour. Could be because the value at those intervals doesn't make sense, or feel random, or because it wouldn't provide the user with a fine enough control being able to go through the whole slider in just 10 swipes. It user will still be able to adjust the slider to any value by double tapping and holding and then moving the finger left or right, bypassing VoiceOver gestures. VoiceOver announces the new value as it changes.

Check for the traversal order of elements in your app. Sometimes, the default top-left to bottom-right order might not be the most logical one. Sometimes, you may consciously want to tweak the order. Some other times, grouping is the answer.
@azzoor has this great video with some advice on how to set up your device for testing accessibility and a ton of tips will get you testing effectively in no time. https://m.youtube.com/watch?v=Ca1H6wF348g&feature=youtu.be
Content © Daniel Devesa Derksen-Staats — Accessibility up to 11!