If you need to send announcement notifications that can step into each other, they will by default, interrupt ongoing announcements. But you can pass attributed strings as parameters too, letting you specify announcements to be queued.
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Support both orientations, if possible. I know not even iOS itself does it, but it hasn't always been like that. You'll create a more robust UI that will be easier to port to iPadOS. And especially, don't force your users to rotate their devices.
A common example where you need to manually configure the button accessibility trait is for some table/collection view cells. These tend to be “buttons” that perform an action, like playing music, or bring the user to a different screen.
Images can automatically scale for accessibility content size categories, by setting the adjustsImageSizeForAccessibilityContentSizeCategory property to true, for any UIImageView you'd like to get its size adjusted. https://developer.apple.com/documentation/uikit/uiaccessibilitycontentsizecategoryimageadjusting/adjustsimagesizeforaccessibilitycontentsizecategory
