Grouping elements with .accessibility(children: .combine) doesn't always generate the best accessibility label. Comma-separating labels might sometimes not be ideal. But you can improve it by tweaking the labels/grouping of its children first.

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An interesting speech attribute for attributed accessibility labels is accessibilitySpeechIPANotation that lets you specify how VoiceOver should pronounce a label with the International Phonetic Alphabet (IPA) notation. https://developer.apple.com/documentation/foundation/nsattributedstring/key/accessibilityspeechipanotation

Potential benefits from grouping logical pieces of information and moving buttons to custom actions: reduce redundancy (by removing repetitive controls) and reduce cognitive load (by making easier to know what item will be affected by each action)

You should convey important information in multiple modes, not just color. If you are still required to do so, at the very least you should complement that info with other modes, like symbols, if the user requested differentiation without color.