This is a small trick I use to compose complex accessibility labels/values when, for a UI component, some elements might not be in all its instances. An array of optional Strings, compact map, and join all elements by a separator, like a comma.

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Do you have a fancy custom loading animation instead of an UIActivityIndicatorView? You may want to check if it has an accessibility label so a VoiceOver user knows that something is happening. Something like "In progress" or "Loading" could work.

When implementing a UISlider, it is a good idea to consider how much the slider value should change when swiping up/down to adjust it. It might not always make sense to do it in 10% increments, which is the default behaviour. Could be because the value at those intervals doesn't make sense, or feel random, or because it wouldn't provide the user with a fine enough control being able to go through the whole slider in just 10 swipes. It user will still be able to adjust the slider to any value by double tapping and holding and then moving the finger left or right, bypassing VoiceOver gestures. VoiceOver announces the new value as it changes.
An alternative layout for large font sizes can be provided with Auto Layout by having three sets of constraints (common, default constraints, and alternative constraints) and activate/deactivate them depending on the content size category.